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Beauty brands including L’Oréal Paris, The Ordinary and Medik8 have introduced PDRN products in 2026, extending an ingredient trend that began in K-beauty. Spate reports 37.2 million average monthly interactions across Google, TikTok and Instagram, but experts caution that evidence for topical PDRN does not match that for injectable use.
L’Oréal Paris, The Ordinary and Medik8 are among a growing mix of beauty brands launching products with PDRN in 2026, taking the ingredient from its K-beauty roots into products sold across price points and categories. The expansion comes as online interest rises, though experts say the evidence for topical PDRN remains more limited than for injectable use.
The launches include L’Oréal Paris Revitalift Filler Hyaluronic PDRN+ Anti-Wrinkle Plumping Serum, which adds hyaluronic acid and what the company describes as its patented biotech-derived PDRN+. The product is marketed for glow, plumpness and smoother-looking skin and has a recommended retail price of £31.99. Claims about absorption and skin effects are the brand’s, rather than independent findings cited in the report.
The Ordinary has made PDRN part of its first eye cream, Lacto-PDRN 4% + B9 Eye Cream, priced at £8.70. The company says its ingredient is made through controlled fermentation of Lactobacillus rhamnosus and was selected for data specific to the eye area. Medik8’s Exo-PDRN Prismatic+ Youthful Vitality Serum, priced at £79, combines vegan PDRN with exosomes. The company lists improvements to visible redness, wrinkles, brightness and skin texture among its claims, citing clinical results.
The report also identifies launches from Clinique, Dior, Byoma, Nip + Fab, Primark and Iconic London, spanning luxury skincare, mass-market ranges and makeup. Iconic London’s Underglaze Long-Wear PDRN Grippy Primer uses plant-derived PDRN. The source material does not provide full product details for every named launch, so their formulas, prices and claims cannot all be compared from the available information.
PDRN Moves Across Beauty Categories
The spread of PDRN shows how a skincare ingredient associated with K-beauty is being adapted for established Western brands and more everyday products. It now appears in serums and eye cream, as well as a makeup primer, giving consumers more ways to encounter the ingredient and brands more opportunities to market it.
Spate’s 2026 Ingredient Trends Report estimates 37.2 million average monthly interactions for PDRN across Google, TikTok and Instagram, with year-on-year growth of 609.8%. It predicts interest will rise a further 34.4% this year. These are engagement estimates and a forecast, not sales figures or evidence that the products work. Spate says K-beauty brands including Medicube, Rejuran, Anua, Genabelle and VT-Cosmetics currently dominate consumer interest.
For shoppers, the launch wave makes it more relevant to distinguish an ingredient’s popularity from evidence for a finished product. Formula and delivery system matter, according to aesthetic doctor and Korean skincare expert Dr Christine Hall, and similar ingredient names may refer to different sources or formulations.
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From Korean Clinics to Topical Products
PDRN stands for polydeoxyribonucleotide, a DNA extract traditionally sourced from salmon sperm cells. The report says plant-based and biotechnology-derived alternatives are increasingly being used. PDRN has been sold in Korean pharmacies and used in skincare, while injectable forms have also been used in clinics.
Hall says the ingredient’s current appeal connects several consumer interests: K-beauty, skin longevity, hydration and support for the skin barrier. She describes a broader move away from harsh or exfoliating approaches toward products positioned around supporting skin’s maintenance and recovery. That is an explanation of the trend, not proof that topical products deliver the same effects as medical use.
The report describes 2026 as a year of launches from both luxury and mass-market brands. Its named examples show how companies are positioning PDRN for different routines, from a targeted eye product to a serum and a long-wear primer.
“While we cannot and should not claim that topical PDRN carries the same regenerative benefits as the injectable form, it has its values in repairing compromised skin.”
— Dr Christine Hall, aesthetic doctor and Korean skincare expert
Topical Evidence Remains Limited
How well topical PDRN works remains less established than the evidence associated with injectable use, Hall says. The source report does not provide a systematic review of clinical research or enough methodological detail to assess the individual brands’ cited tests. Product claims about absorption, firmness, redness or wrinkles therefore remain claims attributed to the companies.
It is also unclear how much of the predicted increase in online interest will translate into purchases, repeat use or measurable consumer outcomes. Spate’s figures combine interactions across three platforms and search, but the source material does not detail the underlying measurement method or the baseline used for its forecast. The listed launches may not represent every PDRN product entering the market.
More Launches and Evidence to Watch
The report points to continued brand activity as companies respond to consumer interest, but it gives no confirmed schedule for upcoming launches or sales data for the products already named. Spate forecasts a further 34.4% rise in interest during 2026; that projection can be compared with later trend data as the year progresses.
For shoppers and industry observers, the next useful signals will be clearer product-level evidence, details about ingredient sourcing and delivery, and whether interest persists beyond launch campaigns. Hall’s guidance is to judge PDRN products as complete formulations rather than by the presence of a trending ingredient alone.
Key Questions
What does PDRN stand for?
PDRN is short for polydeoxyribonucleotide, a DNA extract traditionally sourced from salmon cells. The report says plant-based and biotech-derived alternatives are also entering products.
Which brands are launching PDRN products?
The report names L’Oréal Paris, The Ordinary, Medik8, Clinique, Dior, Byoma, Nip + Fab, Primark and Iconic London, alongside K-beauty brands already associated with the ingredient.
Is topical PDRN proven to work like injectable PDRN?
No equivalence is established in the source material. Hall says topical products should not be claimed to carry the same regenerative benefits as injectable PDRN, and says evidence for topical use is less strong.
How much consumer interest is PDRN attracting?
Spate estimates 37.2 million average monthly interactions across Google, TikTok and Instagram, with 609.8% year-on-year growth. It forecasts another 34.4% rise in interest in 2026; these figures are estimates and a forecast, not sales data.
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